| SLOT | PLAYER | PROJ | PTS |
| QB | Joe Burrow | 19.0 | -- |
| CIN QB · vs PIT · Sun 8:20p |
| RB | Jahmyr Gibbs | 21.6 | -- |
| DET RB · vs NE · Sun 9:30a |
| RB | Ollie Gordon II | 15.0 | -- |
| MIA RB · @IND · Sun 1:00p |
| WR | Drake London | 12.1 | -- |
| ATL WR · vs KC · Sun 1:00p |
| WR | DeMario Douglas | 10.1 | -- |
| NE WR · @DET · Sun 9:30a |
| TE | Brock Bowers | 12.4 | -- |
| LV TE · vs SEA · Sun 4:05p |
| FLEX | Blake Corum | 10.9 | -- |
| LAR RB · @ARI · Sun 4:05p |
| D/ST | Packers D/ST | 5.6 | -- |
| GB D/ST · vs MIN · Sun 1:00p |
| K | Tyler Bass | 11.2 | -- |
| BUF K · @NYJ · Sun 1:00p |
| STARTERS | 118.0 | 0.0 |
| Bench | Matthew Stafford | 17.0 | -- |
| LAR QB · @ARI · Sun 4:05p |
| Bench | DK Metcalf | 9.4 | -- |
| PIT WR · @CIN · Sun 8:20p |
| Bench | Omar Cooper Jr. | 7.6 | -- |
| NYJ WR · vs BUF · Sun 1:00p |
| Bench | Kaelon Black | 7.3 | -- |
| SF RB · @DAL · Sun 4:25p |
| Bench | DeVonta Smith | 0.0 | -- |
| PHI WR · BYE |
| Bench | Davante Adams | 0.0 | -- |
| LAR WR · @ARI · Sun 4:05p |
| Bench | Jonah Coleman | 0.0 | -- |
| DEN RB · BYE |
| Bench | Makai Lemon | 0.0 | -- |
| PHI WR · BYE |
| Bench | Chase McLaughlin | 0.0 | -- |
| TB K · BYE |
| BENCH | 41.2 | 0.0 |
| IR | T. Etienne Jr. | 0.0 | -- |
| NO RB · vs CAR · Sun 1:00p |
| SLOT | PLAYER | PROJ | PTS |
| QB | Trevor Lawrence | 21.5 | -- |
| JAX QB · @TEN · Sun 1:00p |
| RB | K. Walker III | 24.4 | -- |
| KC RB · @ATL · Sun 1:00p |
| RB | C. McCaffrey | 19.4 | -- |
| SF RB · @DAL · Sun 4:25p |
| WR | Malik Nabers | 13.4 | -- |
| NYG WR · vs WSH · Thu 8:15p |
| WR | Tee Higgins | 13.1 | -- |
| CIN WR · vs PIT · Sun 8:20p |
| TE | Trey McBride | 10.5 | -- |
| ARI TE · vs LAR · Sun 4:05p |
| FLEX | Parker Washington | 12.6 | -- |
| JAX WR · @TEN · Sun 1:00p |
| D/ST | Rams D/ST | 8.3 | -- |
| LAR D/ST · @ARI · Sun 4:05p |
| K | Will Reichard | 9.4 | -- |
| MIN K · @GB · Sun 1:00p |
| STARTERS | 132.4 | 0.0 |
| Bench | Tyler Shough | 17.3 | -- |
| NO QB · vs CAR · Sun 1:00p |
| Bench | J.J. McCarthy | 15.6 | -- |
| NYG QB · vs WSH · Thu 8:15p |
| Bench | Jadarian Price | 10.9 | -- |
| SEA RB · @LV · Sun 4:05p |
| Bench | Jalen Coker | 9.4 | -- |
| CAR WR · @NO · Sun 1:00p |
| Bench | Adonai Mitchell | 8.9 | -- |
| NYJ WR · vs BUF · Sun 1:00p |
| Bench | Josh Downs | 7.4 | -- |
| KC WR · @ATL · Sun 1:00p |
| Bench | Wan'Dale Robinson | 6.7 | -- |
| TEN WR · vs JAX · Sun 1:00p |
| Bench | Saints D/ST | 4.8 | -- |
| NO D/ST · vs CAR · Sun 1:00p |
| Bench | R. Stevenson | 0.0 | -- |
| NE RB · @DET · Sun 9:30a |
| BENCH | 81.0 | 0.0 |
| IR | RJ Harvey | 0.0 | -- |
| DEN RB · BYE |